The department Scientific Research contributes to the careful distribution of information about the history of the Kröller-Müller Museum and the collection. An important tool is the publishing of collection catalogues. These publications discuss parts of the collection, such as the Van Gogh collection and the sculpture garden. Of each work the meaning within the work of the artist is discussed, but also the meaning of the work within the collection of the museum, and the history of the work. The publication of the collection catalogues ensures an increasingly precise view of the collection as a whole, and the motivations of the museum's founders as well as their successors.
The department plays an important part in managing the archives and documentation, that form the basis for historical research. The arthistoric department also supports other museum departments, in matters such as conservation, education, presentations of collections, and exhibitions. When researching specific artists, the department regularly cooperates with specialists outside the museum.